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Pharmaceutical excipients

Sorbitol Solution 70%

Liquid polyol for sweetening, moisture retention and formulation use

Sorbitol Solution 70% is an aqueous polyol material used as a liquid sweetener, humectant and formulation vehicle. Its syrup-like consistency makes it useful in oral liquids, creams, pastes and other compatible products. Sorbitol is also known as D-glucitol.

Sorbitol CAS
50-70-4
Concentration
70% product line
Form
Clear syrupy liquid
Supplier illustration of Sorbitol 70% solution held in a glass beaker.
Clear sorbitol solution. Product illustration.
Product overview

Understanding the material

Liquid sorbitol is supplied in different compositions, including crystallising and non-crystallising grades. The name “70%” must be read with the specification: total dry substance and D-sorbitol assay describe different properties. Selecting the right grade involves the concentration basis, related polyols, crystallisation behaviour and intended application—not just the product name.

Identity & properties

Product Identity & Specifications

Chemical identity, physical characteristics and key specifications for Sorbitol Solution 70%.

ParameterDescription / valueBasis / application
MaterialAqueous sorbitol / polyol solutionLiquid excipient
Common synonymD-glucitol solutionSorbitol is a sugar alcohol
Sorbitol CAS number50-70-4Identity of the D-sorbitol component
Sorbitol formulaC₆H₁₄O₆Solute; the solution also contains water
Sorbitol molecular weight182.17 g/molD-sorbitol component
AppearanceClear, colourless, syrupy liquidGeneral liquid-sorbitol description
Nominal concentration70% product designationConfirm dry-substance or assay basis on the offered specification
USP Sorbitol Solution definitionAt least 64.0% D-sorbitolNot interchangeable with 70% total solids
Grade typeCrystallising or non-crystallisingComposition and application dependent
Water compatibilityMixes with waterCheck compatibility in the complete formulation
Density / viscosityReported with test temperatureUse the offered grade’s specification
Purity controlsRelated polyols, sugars, EG/DEG and microbial qualityLimits follow the selected pharmaceutical specification

Identity and published standard

USP–NF: Sorbitol Solution

The published definition specifies an aqueous solution containing at least 64.0% D-sorbitol. Other sugars and polyhydric alcohols may be present. The 70% product designation and its concentration basis must be read separately in the offered specification.

View published monograph

A published standard describes the material; conformity of the offered grade is confirmed through its current specification and COA.

For further information and current COA/specification, please contact us.

Request current COA & specification
Where it is used

Applications & functional benefits

01

Oral liquid formulations

Provides bulk sweetness and a liquid vehicle in suitable syrups and suspensions. Product development should assess taste, dissolved solids, viscosity and compatibility with the active and other excipients.

02

Creams, pastes and semisolids

Functions as a humectant to support moisture retention. The selected concentration contributes to the water phase and must be included in the formulation’s total water and solids balance.

03

Softgel and other specialist systems

Certain non-crystallising liquid-polyol grades are used in softgel plasticiser systems. This application requires a grade selected for the gelatin system; the generic 70% name does not identify that grade.

Choose the right material

Understanding the concentration and grade

TermWhat it describesWhy it matters
Total solids / dry substanceAll dissolved non-water materialCan include D-sorbitol plus other polyols or sugars.
D-sorbitol assayThe amount of the specific sorbitol componentCheck whether the result is on solution or dry-substance basis.
Crystallising gradeA liquid grade with its own crystallisation characteristicsSelect against the finished product and storage conditions.
Non-crystallising gradeA formulation of polyols selected for reduced crystallisationDo not assume it has the same D-sorbitol concentration as another grade.
Manufacturing considerations

Formulation & processing

Balance the formulation water

The liquid ingredient contributes both dissolved solids and water. Use the stated composition when replacing a powder or changing the liquid grade so that the batch water balance remains correct.

Specify transfer conditions

Viscosity and density data need their measurement temperature. Use the relevant values when discussing pumping, mixing, weighing or volume-based transfer with the production team.

Manage cleanliness and compatibility

Use clean, compatible transfer equipment and keep opened containers protected. Assess microbiological quality and preservation in the finished formulation rather than assuming the raw solution makes the whole product self-preserving.

Quality review

What to check in the specification

  • D-sorbitol assay and total solids: retain the test method and reporting basis for each.
  • Related polyols and reducing sugars: review the composition relevant to the formulation.
  • Ethylene glycol and diethylene glycol: obtain applicable impurity-control evidence for pharmaceutical use.
  • Microbial limits: agree requirements appropriate to the intended formulation and handling.
  • Viscosity, colour and crystallisation behaviour: evaluate the offered grade under its stated test conditions.

Current product documentation

Request the current COA, full specification, SDS and concentration/solids information. For pharmaceutical use, include the required microbial and EG/DEG documentation in your enquiry.

Request documents for Sorbitol Solution 70%
Supply & handling

Packing, storage & handling

Packing and quotation details

Include the required delivery quantity and preferred drum or bulk-container arrangement in your enquiry. SBS will confirm the offered container, net weight, manufacturer, origin and delivery terms. Ask for a sample if viscosity or crystallisation behaviour needs to be assessed before purchase.

Storage and safe handling

Keep containers closed and prevent contamination during sampling and transfer. Follow the manufacturer’s storage-temperature and shelf-life instructions. If crystallisation or a change in appearance occurs, seek the supplier’s handling guidance before applying heat or returning the material to use.

Product questions

Frequently asked questions

Does 70% always mean 70% pure D-sorbitol?

No. A grade may express the designation in terms of total solids. Check the D-sorbitol assay and its reporting basis separately.

Can any liquid sorbitol be used in softgel capsules?

No. Softgel systems need a suitable plasticiser grade and formulation qualification. Tell SBS that the intended application is softgel manufacture.

Which documents are most useful for pharmaceutical use?

Request the batch COA, full specification, SDS, concentration details, applicable EG/DEG controls and microbial results. State the required pharmacopoeial grade.

Technical information sources

Need more information?

Contact SBS for further product details, current COA, specification, packing and a quotation for your requirement.

Contact SBS for details and documents